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Structural States of a Brain Receptor Revealed
NIH Research Matters
 
Glutamate Receptors: Mechanistic Twists and Turns
Nature Chemical Biology
 
NIH Scientists Visualize Structures of Brain Receptors
NIH News
 
Molecular Mechanism Identified for Neurotransmitter Receptor in the Brain
NCI News Note
 
Fellows Award for Research Excellence (FARE)
Awarded to Doreen Matthies and Gabriel Frank
 
PrEParing for HIV: An Epidemic Initiatives Intervention
University of California Television
 
Rift Widens Over Structure of HIV's Molecular Anchor
Nature News
 
HIV and Influenza Share a Similar Structural Blueprint
NCI News Note
 
Protein Machines at Work
NIH Director's Blog
 
Small Antibody Fragments Bind and Neutralize HIV
NCI in the Journals
 
The Living Lab: Navigating into Cells
NCI News
 
Cell Picture Show: Viruses
Cell
 
Unraveling the
structural basis of
HIV-1 neutralization

Future Microbiology
 
Structure of the pre-fusion state of the HIV Env trimer determined
IAVI Report
 
HIV Protein Strikes a Fleeting Pose
NIH Research Matters
 
How HIV Hijacks the Immune System
National Public Radio
 
NCI scientists image proteins on HIV surface
NCI News Note
 
NIH-FEI Living Lab for Structural Biology
1. NIH Press Release
2. Chemical and Engineering News
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2012 Intramural AIDS Research Fellowship
Awarded to Joel Meyerson
NIH Office of Intramural Training
 
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Remote Data Acquisition
ASBMB Today
 
Molecular Structures of HIV Glycoproteins
Journal of Visualized Experiments
 
Cell Picture Show: HIV
Cell
 
2011 Intramural AIDS Research Fellowship
Awarded to Gabriel Frank
 

3-D Structure of Dendritic Cell-T Cell Virological Synapses Revealed
IAVI Report

 
HIV Spread in 3D
Nature Research Highlights
 
Visualizing High-Efficiency HIV Transfer
NCI in the Journals
 
Students Accelerate HIV Research
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The Beauty Behind the Beasts
IAVI Report
 
A Conversation with Dr. Sriram Subramaniam
NCI Cancer Bulletin
 
HIV Molecular Entry Claw
1. NIH News
2. NIH Research Matters

 

 

PUBLICATIONS

Selected Publications: 1999 - 2014

   

2012-2014 | 2010-2011 | 2005-2009 | 1999-2004


2014

 
Annu Rev Virol. In press.
Risco C, de Castro IF, Sanz-Sanchez L, Narayan K, Grandinetti G, and Subramaniam S. (2014) Three-dimensional imaging of viral infections.
Annu Rev Virol. In press.
 
Nature. 2014 Aug 3.
Meyerson JR, Kumar J, Chittori S, Rao P, Pierson J, Bartesaghi A, Mayer ML, and Subramaniam, S. (2014) Structural mechanism of glutamate receptor activation and desensitization.
Nature. 2014 Aug 3. doi: 10.1038/nature13603. [Epub ahead of print]
 
Proc Natl Acad Sci U S A. 2014 Jul 28.
Bartesaghi A, Matthies D, Banerjee S, Merk A, and Subramaniam S. (2014) Structure of -galactosidase at 3.2- resolution obtained by cryo-electron microscopy.
Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11709-14. doi: 10.1073/pnas.1402809111. Epub 2014 Jul 28.
 
JJ Virol. 2014 Jul 9.
Tran EEH, Simmons JA, Bartesaghi A, Shoemaker CJ, Nelson E, White JM, and Subramaniam S. (2014) Spatial localization of the Ebola glycoprotein mucin-like domain using cryo-electron tomography.
J Virol. 2014 Sep;88(18):10958-62. doi:10.1128/JVI00870-14. Epub 2014 Jul 9.
 
J Virol. 2014 Jun 25.
Do T, Murphy G, Earl LA, Del Prete GQ, Grandinetti G, Li G, Estes J, Rao P, Trubey C, Thomas J, Spector J, Bliss D, Nath A, Lifson JD, and Subramaniam S. (2014) 3D imaging of HIV-1 virological synapses reveals membrane architectures involved in virus transmission.
J Virol. 2014 Sep;88(18):10327-39. doi:10.1128/JVI00788-14. Epub 2014 Jun 25.
 
Advan. Imaging Electron Physics. In press.
Agard D, Cheng Y, Glaeser RM, and Subramaniam S. (2014) Single particle cryo-electron microscopy: progress, challenges, and perspectives for further improvement.
Advan. Imaging Electron Physics. In press.
 
J Struct Biol. 2013 Dec 1
Narayan K, Danielson CM, Lagarec K, Lowekamp BC, Coffman P, Laquerre A, Phaneuf MW, Hope TJ, and Subramaniam S. (2014) Multi-resolution correlative focused ion beam scanning electron microscopy: Applications to cell biology.
J Struct Biol. 2014 Mar;185(3):278-84. doi: 10.1016/j.jsb.2013.11.008. Epub 2013 Dec 1.

2013

 
PLoS One. 2013 Nov 26
Wang T, Choi E, Monaco MC, Campanac E, Medynets M, Do T, Rao P, Johnson KR, Elkahloun AG, Von Geldern G, Johnson T, Subramaniam S, Hoffman D, Major E, and Nath A. (2013) Derivation of neural stem cells from human adult peripheral CD34+ cells for an autologous model of neuroinflammation.
PLoS One. 2013 Nov 26;8(11):e81720. doi: 10.1371/journal.pone.0081720. eCollection 2013.
 
Proc Natl Acad Sci U S A. 2013 Nov 5
Subramaniam S. (2013) Structure of trimeric HIV-1 envelope glycoproteins.
Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):E4172-4. doi: 10.1073/pnas.1313802110. Epub 2013 Oct 8.
 
PLoS One. 2013 Nov 7
Gustchina E, Li M, Ghirlando R, Schuck P, Louis JM, Pierson J, Rao P, Subramaniam S, Gustchina A, Clore GM, and Wlodawer A. (2013) Complexes of Neutralizing and Non-Neutralizing Affinity Matured Fabs with a Mimetic of the Internal Trimeric Coiled-Coil of HIV-1 gp41.
PLoS One. 2013 Nov 7;8(11):e78187. doi: 10.1371/journal.pone.0078187.
 
Nat Struct Mol Biol. 2013 Oct 23
Bartesaghi A, Merk A, Borgnia MJ, Milne JLS, and Subramaniam S. (2013) Prefusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy.
Nat Struct Mol Biol. 2013 Dec;20(12):1352-7. doi: 10.1038/nsmb.2711. Epub 2013 Oct 23.
 
 Struct Biol. 2013 Sep
Wu X, Subramaniam S, Case DA, Wu KW, and Brooks BR. (2013) Targeted conformational search with map-restrained self-guided Langevin dynamics: Application to flexible fitting into electron microscopic density maps images.
J Struct Biol. 2013 Sep;183(3):429-40. doi: 10.1016/j.jsb.2013.07.006. Epub 2013 Jul 20.
 
Trends Microbiol. 2013 Jul 11.
Earl LA, Lifson JD, and Subramaniam S. (2013) Catching HIV 'in the act' with 3D electron microscopy.
Trends Microbiol. 2013 Aug;21(8):397-404. doi: 10.1016/j.tim.2013.06.004. Epub 2013 Jul 11.
 
J Virol. 2013 Apr 17
Harris AK, Bartesaghi A, Milne JLS, and Subramaniam S. (2013) HIV-1 envelope glycoprotein trimers display open quaternary conformation when bound to the gp41 MPER-directed broadly neutralizing antibody Z13e1.
J Virol. 2013 Jun;87(12):7191-6. doi: 10.1128/JVI.03284-12. Epub 2013 Apr 17.
 
Curr Opin Struct Biol. 2013 Apr 18
Merk A and Subramaniam S. (2013) HIV-1 envelope glycoprotein structure.
Curr Opin Struct Biol. 2013 Apr;23(2):268-76. doi: 10.1016/j.sbi.2013.03.007. Epub 2013 Apr 18.
 
roc Natl Acad Sci U S A. 2013 Mar 25.
Schauder DM, Kuybeda O, Zhang J, Klymko K, Bartesaghi A, Borgnia MJ, Mayer ML, and Subramaniam S. (2013) Glutamate receptor desensitization is mediated by changes in quaternary structure of the ligand binding domain.
Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):5921-6. doi: 10.1073/pnas.1217549110. Epub 2013 Mar 25.
 
Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4592-7. doi: 10.1073/pnas.1214913110. Epub 2013 Mar 4.
Harris AK, Meyerson JR, Matsuoka Y, Kuybeda O, Moran A, Bliss D, Das SR, Yewdell JW, Sapiro G, Subbarao K, and Subramaniam S. (2013) Structure and accessibility of HA trimers on intact 2009 H1N1 pandemic influenza virus to stem region-specific neutralizing antibodies.
Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4592-7. doi: 10.1073/pnas.1214913110. Epub 2013 Mar 4.
 
FEBS J. 2012 Nov 26
Milne JLS, Borgnia MJ, Bartesaghi A, Tran EEH, Earl LA, Schauder DM, Lengyel J, Pierson J, Patwardhan A, and Subramaniam S. (2013) Cryo-electron microscopy: A primer for the non-microscopist.
FEBS J. 2013 Jan;280(1):28-45. doi: 10.1111/febs.12078.
 
Proc Natl Acad Sci U S A. 2013 Jan 8
Meyerson JR, Tran EEH, Kuybeda O, Chen W, Dimitrov DS, Gorlani A, Verrips T, Lifson JD, and Subramaniam S. (2013) Molecular structures of trimeric HIV-1 Env in complex with small antibody derivatives.
Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):513-8. doi: 10.1073/pnas.1214810110.
 
The Encyclopedia of Biological Chemistry. Lennarz WJ and Lane MD, eds. vol. 4, pp. 321-328. Waltham, MA: Academic Press.
Milne, JLS. (2013) Structure and Regulation of Pyruvate Dehydrogenases.
The Encyclopedia of Biological Chemistry. Lennarz WJ and Lane MD, eds. vol. 4, pp. 321-328. Waltham, MA: Academic Press.

2012

 
Resonance J Sci Edu. 2012 Dec;17(12)1157-64
Karnik S and Subramaniam S. (2012) There is no overkill in biochemistry.
Resonance J Sci Edu. 2012 Dec;17(12)1157-64. doi: 10.1007/s12045-012-0132-6.
 
Nat Struct Mol Biol. 2012 Dec 5;19(12):1203-7. doi: 10.1038/nsmb.2426.
Patwardhan A, Carazo JM, Carragher B, Henderson R, Heymann JB, Hill E, Jensen GJ, Lagerstedt I, Lawson CL, Ludtke SJ, Mastronarde D, Moore WJ, Roseman A, Rosenthal P, Sorzano CO, Sanz-Garcia E, Scheres SH, Subramaniam S, Westbrook J, Winn M, Swedlow JR, and Kleywegt GJ. (2012) Data management challenges in three-dimensional EM.
Nat Struct Mol Biol. 2012 Dec 5;19(12):1203-7. doi: 10.1038/nsmb.2426.
 
Structure. 2012 Dec 5;20(12):2003-13. doi: 10.1016/j.str.2012.10.016.
Bartesaghi A, Lecumberry F, Sapiro G, and Subramaniam S. (2012) Protein secondary structure determination by constrained single particle cryo-electron tomography.
Structure. 2012 Dec 5;20(12):2003-13. doi: 10.1016/j.str.2012.10.016.
 
J Struct Biol. 2012 Oct 27
Kuybeda O, Frank GA, Bartesaghi A, Borgnia M, Subramaniam S, and Sapiro G. (2012) A collaborative framework for 3D alignment and classification of heterogeneous subvolumes in cryo-electron tomography.
J Struct Biol. 2012 Oct 27. pii: S1047-8477(12)00292-4. doi: 10.1016/j.jsb.2012.10.010. [Epub ahead of print].
 
IEEE Trans Med Imaging. 2012 Aug 20
Gopinath A, Xu G, Ress D, Oktem O, Subramaniam S, Bajaj C. (2012) Shape-based regularization of electron tomographic reconstruction.
IEEE Trans Med Imaging. 2012 Aug 20; [Epub ahead of print].
 
IEEE Comput Graph. 2012 Sep; 32(5):39-49.
Yoo TS, Bliss D, Lowekamp BC, Chen DT, Muphy GE, Narayan K, Hartnell LM, Do T, and Subramaniam S. (2012) Visualizing cells and humans in 3D: Biomedical image analysis at nanometer and meter scales.
IEEE Comput Graph. 2012 Sep; 32(5):39-49.
 
PLoS Pathog. 2012 Jul 13;8(7): e1002797.
Tran EEH, Borgnia MJ, Kuybeda O, Shauder DM, Bartesaghi A, Frank GA, Sapiro G, Milne JLS, Subramaniam S. (2012) Structural mechanism of trimeric HIV-1 envelope glycoprotein activation.
PLoS Pathog. 2012 Jul;8(7): e1002797.
 
Encyclopedia of Biophysics: Chemoreceptor arrays
Venkatesh MJ and Subramaniam S. (2012) Chemoreceptor arrays.
Encyclopedia of Biophysics. Gordon GKC, ed. Springer (NY).
doi: 10.1007/978-3-642-16712-6_79.
 
J Struct Biol. 2012 May;178(2):98-107.
Narayan K, Prosa T, Fu J, Kelly TF, and Subramaniam S. (2012) Chemical mapping of mammalian cells by atom probe tomography.
J Struct Biol. 2012 May;178(2):98-107.
 
J Struct Biol. 2012 May;178(2):165-76.
Frank GA, Bartesaghi A, Kuybeda O, Borgnia MJ, White TA, Sapiro G and Subramaniam S. (2012) Computational separation of conformational heterogeneity using cryo-electron tomography and 3D sub-volume averaging.
J Struct Biol. 2012 May;178(2):165-76.
   
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