Lab Members

Sriram Subramaniam

Sriram Subramaniam

Senior Investigator and Chief, Biophysics Section
Tel: 240-760-6384
ss1@nih.gov

Sriram Subramaniam received his Ph.D. in Physical Chemistry from Stanford University and completed postdoctoral training in the Departments of Chemistry and Biology at M.I.T. He is chief of the Biophysics Section in the Laboratory of Cell Biology at the Center for Cancer Research, National Cancer Institute. He holds a visiting faculty appointment at the Johns Hopkins University School of Medicine.
 

Jacqueline Milne

Jacqueline Milne

Senior Associate Scientist
Tel: 240-760-6381
jmilne@nih.gov

Jacqueline Milne obtained her Ph.D. in biology from York University, Toronto and received her postdoctoral research training with Peter Devreotes in the Department of Biological Chemistry, The Johns Hopkins School of Medicine, and with Richard Henderson in the Laboratory of Molecular Biology, Medical Research Council, Cambridge, England. She is the head of the Electron Microscopy Core within the Laboratory of Cell Biology at the Center for Cancer Research, National Cancer Institute.

Lisa Hartnell

Lisa Hartnell

Electron Microscopist
Tel: 240-760-6369
hartnell@mail.nih.gov

Lisa Hartnell is a specialist in electron microscopy, with extensive academic and industry experience in visualization and characterization of biological and non-biological materials by transmission and scanning electron microscopy. In the laboratory, she carries out 3D cellular and tissue imaging projects using FIB-SEM and TEM.

Reinhard Grisshammer

Staff Scientist
Tel: 240-781-4031
reinhard.grisshammer2@nih.gov

Reinhard Grisshammer received his Ph.D. degree from the Johann-Wolfgang Goethe University in Frankfurt, Germany. He did post-doctoral work with Richard Henderson in Cambridge, England, where he focused on structural work of G-protein-coupled receptors. In 2001, he joined the NIH, studying mechanistic aspects of G-protein-coupled receptor activation.

Sagar Chittori

Sagar Chittori

Post-doctoral Fellow
Tel: 240-760-6359
chittoris@mail.nih.gov

Sagar Chittori earned his Ph.D. in structural biology from Indian Institute of Science, India, and has research experience in cellular and molecular biology, biochemistry, X-ray crystallography, and computational biology. His current research in the laboratory focuses on the structure and function of protein complexes using cryo-electron microscopy.

Joseph Darling

Joe Darling

Post-doctoral Fellow
Tel: 240-760-6361
joseph.darling@nih.gov

Joe Darling earned his Ph.D. in biochemistry; his research background involves membrane protein expression and enzymology. His work in the laboratory involves high resolution structural analysis of membrane proteins.

Jean-Philippe Demers

Jean-Philippe Demers

Post-doctoral Fellow
Tel: 240-760-6362
jpdemers@nih.gov

Jean-Philippe Demers earned a doctorate in physics, and has research experience in structural biology and biophysics, especially in NMR techniques. He is interested in the development of computational methods for sorting conformational heterogeneity of molecular complexes, and in integrative approaches to combine EM data with information from complementary structural biology techniques.

Jana Ognjenovic

Jana Ognjenović

Post-doctoral Fellow
Tel: 240-760-6569
ognjenovicj2@mail.nih.gov

Jana Ognjenović earned her Ph.D. studying immune responses to environmental allergens, and has research experience in protein biochemistry and X-ray crystallography. Her interests in the lab include the structure and function of large macromolecular assemblies.

Xing Zhu

Post-doctoral Fellow
Tel: 240-760-6374
xing.zhu@nih.gov

Xing Zhu earned his Ph.D. in biochemistry and molecular biology, and specializing in structural analysis of CRISPR-Cas systems by X-ray crystallography. His current research interests in the lab include high resolution structural analysis of protein complexes by cryo-electron microscopy.

Brian Caffrey

Brian Caffrey

Graduate Student
University College Dublin
Tel: 240-760-2361
brian.caffrey@nih.gov

Brian Caffrey holds a baccalaureate degree in chemistry, and is currently pursuing a Ph.D. at University College Dublin. He has research experience in biochemistry and phage display; his current research focuses on the 3D structure of cells and tissues, and on the structural analysis of nanoparticles.

Andrew Wilbur

Post-baccalaureate Fellow
University of California, San Diego
Tel: 240-760-7344
andrew.wilbur@nih.gov

Andrew Wilbur received his baccalaureate degree in Chemistry and Biochemistry from the University of California, San Diego. The current focus of his research in the laboratory is high resolution 3D structure determination of small complexes by cryo-electron microscopy.

Alan Merk

Alan Merk

Structural Biologist
Contractor
Tel: 240-760-6378
alan.merk@nih.gov

Alan Merk earned his degree in economics, and has a keen interest in the structural biology of HIV. In the laboratory, he specializes in high resolution image collection for single particle cryo-electron microscopy and cryo-electron tomography on the Titan Krios electron microscopes.

Joseph Finney

Engineer
Contractor
Tel: 240-760-7198
joseph.finney@nih.gov

Joseph Finney earned his baccalaureate degree in industrial and systems engineering, and specializes in networking, and software and systems design. His interest in the lab relates to the creation of robust, streamlined workflows for cryo-electron microscopic imaging and data analysis.

Andrei Florescu

Andrei Florescu

Biologist
Contractor
Tel: 240-760-6367
andrei.florescu@nih.gov

Andrei Florescu’s scientific background is in biology and dentistry. He has a particular interest in the culture of primary cells. His work in the laboratory focuses on scientific and logistical support for many aspects of the research program.

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