Senior Investigator and Chief, Biophysics Section
Sriram Subramaniam received his Ph.D. in Physical Chemistry from Stanford University and completed postdoctoral training in the Departments of Chemistry and Biology at M.I.T. He is chief of the Biophysics Section in the Laboratory of Cell Biology at the Center for Cancer Research, National Cancer Institute. He holds a visiting faculty appointment at the Johns Hopkins University School of Medicine.
Senior Associate Scientist
Jacqueline Milne obtained her Ph.D. in biology from York University, Toronto and received her postdoctoral research training with Peter Devreotes in the Department of Biological Chemistry, The Johns Hopkins School of Medicine, and with Richard Henderson in the Laboratory of Molecular Biology, Medical Research Council, Cambridge, England. She is the head of the Electron Microscopy Core within the Laboratory of Cell Biology at the Center for Cancer Research, National Cancer Institute.
Alberto Bartesaghi earned his Ph.D. in electrical engineering, and specializes in computational technologies for automation and image processing. He is responsible for designing, automating and optimizing image processing workflows, and for managing the computational resources of the group.
Erin Tran earned her Ph.D. in microbiology, and is primarily interested in host-pathogen interactions, and the structural mechanisms behind pathogenesis and virulence factors. Her work focuses on the viral envelope glycoprotein structure, including those from HIV and Ebola.
Lisa Hartnell is a specialist in electron microscopy, with extensive academic and industry experience in visualization and characterization of biological and non-biological materials by transmission and scanning electron microscopy. In the laboratory, she carries out 3D cellular and tissue imaging projects using FIB-SEM and TEM.
Doreen Matthies earned her Ph.D. in biochemistry, and has research experience in biochemistry, structural and molecular biology, and X-ray crystallography. Her work in the laboratory involves using single particle cryo-electron microscopy to study structures of membrane protein complexes.
Sagar Chittori earned his Ph.D. in structural biology from Indian Institute of Science, India, and has research experience in cellular and molecular biology, biochemistry, X-ray crystallography, and computational biology. His current research in the laboratory focuses on the structure and function of protein complexes using cryo-electron microscopy.
Joe Darling earned his Ph.D. in biochemistry; his research background involves membrane protein expression and enzymology. His work in the laboratory involves high resolution structural analysis of membrane proteins.
Jean-Philippe Demers earned a doctorate in physics, and has research experience in structural biology and biophysics, especially in NMR techniques. He is interested in the development of computational methods for sorting conformational heterogeneity of molecular complexes, and in integrative approaches to combine EM data with information from complementary structural biology techniques.
Jana Ognjenović earned her Ph.D. studying immune responses to environmental allergens, and has research experience in protein biochemistry and X-ray crystallography. Her interests in the lab include the structure and function of large macromolecular assemblies.
University College Dublin
Brian Caffrey holds a baccalaureate degree in chemistry, and is currently pursuing a Ph.D. at University College Dublin. He has research experience in biochemistry and phage display; his current research focuses on the 3D structure of cells and tissues, and on the structural analysis of nanoparticles.
Tai Wei Guo
Tai Wei Guo received her baccalaureate degree in biological sciences, and her background is in molecular virology. The current focus of her research in the laboratory is on the image processing of cryo-EM data, including single particle analysis of small protein complexes.
Andrei Florescu’s scientific background is in biology and dentistry. He has a particular interest in the culture of primary cells. His work in the laboratory focuses on scientific and logistical support for many aspects of the research program.
Science Writer/ Editor
Lesley Earl earned her Ph.D. in cellular and molecular pathology, and has research experience in immunology, glycobiology, and development, as well as an interest in writing and communications. She is responsible for managing the communications aspects of the research progress of the lab.