Lab Members

Sriram Subramaniam

Sriram Subramaniam

Senior Investigator and Chief, Biophysics Section
Tel: 240-760-6384
ss1@nih.gov

Sriram Subramaniam received his Ph.D. in Physical Chemistry from Stanford University and completed postdoctoral training in the Departments of Chemistry and Biology at M.I.T. He is chief of the Biophysics Section in the Laboratory of Cell Biology at the Center for Cancer Research, National Cancer Institute. He holds a visiting faculty appointment at the Johns Hopkins University School of Medicine.
 

Jacqueline Milne

Jacqueline Milne

Senior Associate Scientist
Tel: 240-760-6381
jmilne@nih.gov

Jacqueline Milne obtained her Ph.D. in biology from York University, Toronto and received her postdoctoral research training with Peter Devreotes in the Department of Biological Chemistry, The Johns Hopkins School of Medicine, and with Richard Henderson in the Laboratory of Molecular Biology, Medical Research Council, Cambridge, England. She is the head of the Electron Microscopy Core within the Laboratory of Cell Biology at the Center for Cancer Research, National Cancer Institute.

Alberto Bartesaghi

Alberto Bartesaghi

Associate Scientist
Tel: 240-760-6351
bartesaghia@mail.nih.gov

Alberto Bartesaghi earned his Ph.D. in electrical engineering, and specializes in computational technologies for automation and image processing. He is responsible for designing, automating and optimizing image processing workflows, and for managing the computational resources of the group.

Lisa Hartnell

Lisa Hartnell

Electron Microscopist
Tel: 240-760-6369
hartnell@mail.nih.gov

Lisa Hartnell is a specialist in electron microscopy, with extensive academic and industry experience in visualization and characterization of biological and non-biological materials by transmission and scanning electron microscopy. In the laboratory, she carries out 3D cellular and tissue imaging projects using FIB-SEM and TEM.

Erin Tran

Erin Tran

Staff Scientist
Tel: 240-760-6386
tranee@mail.nih.gov

Erin Tran earned her Ph.D. in microbiology, and is primarily interested in host-pathogen interactions, and the structural mechanisms behind pathogenesis and virulence factors. Her work focuses on the viral envelope glycoprotein structure, including those from HIV and Ebola.

Reinhard Grisshammer

Staff Scientist
Tel: 240-781-4031
reinhard.grisshammer2@nih.gov

Reinhard Grisshammer received his Ph.D. degree from the Johann-Wolfgang Goethe University in Frankfurt, Germany. He did post-doctoral work with Richard Henderson in Cambridge, England, where he focused on structural work of G-protein-coupled receptors. In 2001, he joined the NIH, studying mechanistic aspects of G-protein-coupled receptor activation.

Doreen Matthies

Doreen Matthies

Post-doctoral Fellow
Tel: 240-760-6377
doreen.matthies@nih.gov

Doreen Matthies earned her Ph.D. in biochemistry, and has research experience in biochemistry, structural and molecular biology, and X-ray crystallography. Her work in the laboratory involves using single particle cryo-electron microscopy to study structures of membrane protein complexes.

Sagar Chittori

Sagar Chittori

Post-doctoral Fellow
Tel: 240-760-6359
chittoris@mail.nih.gov

Sagar Chittori earned his Ph.D. in structural biology from Indian Institute of Science, India, and has research experience in cellular and molecular biology, biochemistry, X-ray crystallography, and computational biology. His current research in the laboratory focuses on the structure and function of protein complexes using cryo-electron microscopy.

Joseph Darling

Joe Darling

Post-doctoral Fellow
Tel: 240-760-6361
joseph.darling@nih.gov

Joe Darling earned his Ph.D. in biochemistry; his research background involves membrane protein expression and enzymology. His work in the laboratory involves high resolution structural analysis of membrane proteins.

Jean-Philippe Demers

Jean-Philippe Demers

Post-doctoral Fellow
Tel: 240-760-6362
jpdemers@nih.gov

Jean-Philippe Demers earned a doctorate in physics, and has research experience in structural biology and biophysics, especially in NMR techniques. He is interested in the development of computational methods for sorting conformational heterogeneity of molecular complexes, and in integrative approaches to combine EM data with information from complementary structural biology techniques.

Jana Ognjenovic

Jana Ognjenović

Post-doctoral Fellow
Tel: 240-760-6569
ognjenovicj2@mail.nih.gov

Jana Ognjenović earned her Ph.D. studying immune responses to environmental allergens, and has research experience in protein biochemistry and X-ray crystallography. Her interests in the lab include the structure and function of large macromolecular assemblies.

Xing Zhu

Post-doctoral Fellow
Tel: 240-760-6374
xing.zhu@nih.gov

Xing Zhu earned his Ph.D. in biochemistry and molecular biology, and specializing in structural analysis of CRISPR-Cas systems by X-ray crystallography. His current research interests in the lab include high resolution structural analysis of protein complexes by cryo-electron microscopy.

Brian Caffrey

Brian Caffrey

Graduate Student
University College Dublin
Tel: 240-760-2361
brian.caffrey@nih.gov

Brian Caffrey holds a baccalaureate degree in chemistry, and is currently pursuing a Ph.D. at University College Dublin. He has research experience in biochemistry and phage display; his current research focuses on the 3D structure of cells and tissues, and on the structural analysis of nanoparticles.

Andrew Wilbur

Post-baccalaureate Fellow
University of California, San Diego
Tel: 240-760-7344
andrew.wilbur@nih.gov

Andrew Wilbur received his baccalaureate degree in Chemistry and Biochemistry from the University of California, San Diego. The current focus of his research in the laboratory is high resolution 3D structure determination of small complexes by cryo-electron microscopy.

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