Publications

Glancy B, Hartnell LM, Combs CA, Fenmou A, Sun J, Murphy E, Subramaniam S, and Balaban RS.
Power Grid Protection of the Muscle Mitochondrial Reticulum.
Cell Rep. 2017 Apr 18;19(3):487-496. doi: 10.1016/j.celrep.2017.03.063.

Pubmed

Meyerson JR, Chittori S, Merk A, Rao P, Han TH, Serpe M, Mayer ML, and Subramaniam S.
Structural basis of kainate subtype glutamate receptor desensitization.
Nature. 2016 Sep 22;537(7621):567-571. doi: 10.1038/nature19352. Epub 2016 Aug 31.

Pubmed

Puppala AK, French RL, Matthies D, Baxa U, Subramaniam S, and Simonović M.
Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase.
Sci Rep. 2016 Aug 31;6:32563. doi: 10.1038/srep32563.

Pubmed

Subramaniam S, Earl LA, Falconieri V, Milne JLS, and Egelman EH.
Resolution advances in cryo-EM enable application to drug discovery.
Curr Opin Struct Biol. 2016 Dec;41:194-202. doi: 10.1016/j.sbi.2016.07.009. Epub 2016 Aug 20.

Pubmed

Earl LA and Subramaniam S.
Cryo-EM of viruses and vaccine design.
Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):8903-5. doi: 10.1073/pnas.1609721113. Epub 2016 Aug 1.

Pubmed

Stuart DI, Subramaniam S, and Abrescia NGA.
The democratization of cryo-EM.
Nat Methods. 2016 Jul 28;13(8):607-8. doi: 10.1038/nmeth.3946.

Pubmed

Tran EE, Nelson EA, Bonagiri P, Simmons JA, Shoemaker CJ, Schmaljohn CS, Kobinger GP, Zeitlin L, Subramaniam S, White JM.
Mapping of Ebolavirus Neutralization by Monoclonal Antibodies in the ZMapp Cocktail Using Cryo-Electron Tomography and Studies of Cellular Entry.
J Virol. 2016 Aug 12;90(17):7618-27. doi: 10.1128/JVI.00406-16. Epub 2016 Jun 8.

Pubmed

Merk A, Bartesaghi A, Banerjee S, Falconieri V, Rao P, Davis M, Pragani R, Boxer M, Earl LA, Milne JLS, and Subramaniam S.
Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Cell. 2016 Jun 16;165(7):1698-1707. doi:10.1016/j.cell.2016.05.040. Epub 2016 May 26.

Pubmed

Frank GA, Shukla S, Rao P, Borgnia MJ, Bartesaghi A, Merk A, Mobin A, Esser L, Earl LA, Gottesman MM, Xia D, Ambudkar SV, and Subramaniam S.
Cryo-EM analysis of the conformational landscape of human P-glycoprotein (ABCB1) during its catalytic cycle.
Mol Pharmacol. 2016 Jul;90(1):35-41. doi: 10.1124/mol.116.104190. Epub 2016 May 11.

Pubmed

Borgnia MJ, Banerjee S, Merk A, Matthies D, Bartesaghi A, Rao P, Pierson J, Earl LA, Falconieri V, Subramaniam S, and Milne JLS.
Using cryo-EM to map small ligands on dynamic metabolic enzymes: studies with glutamate dehydrogenase.
Mol Pharmacol. 2016 Jun;89(6):645-51. doi: 10.1124/mol.116.103382. Epub 2016 Apr 1.

Pubmed

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