Publications

Guo TW, Bartesaghi A, Yang H, Falconieri V, Rao P, Merk A, Eng ET, Raczkowski AM, Fox T, Earl LA, Patel DJ, Subramaniam S.
Cryo-EM structures reveal mechanism and inhibition of DNA targeting by a CRISPR-Cas surveillance complex.
Cell. 2017 Oct 5;171(2):414-426.e12. doi: 10.1016/j.cell.2017.09.006

Pubmed

Wohlbold TJ, Podolsky KA, Chromikova V, Kirkpatrick E, Falconieri V, Meade P, Amanat F, Tan J, tenOever BR, Tan GS, Subramaniam S, Palese P, and Krammer F.
Broadly protective murine monoclonal antibodies against influenza B virus target highly conserved neuraminidase epitopes.
Nat Microbiol. 2017 Oct;2(10):1415-1424. doi: 10.1038/s41564-017-0011-8. Epub 2017 Aug 21.

Pubmed

Patwardhan A, Brandt R, Butcher SJ, Collinson L, Gault D, Grünewald K, Hecksel C, Huiskonen JT, Iudin A, Jones ML, Korir PK, Koster AJ, Lagerstedt I, Lawson CL, Mastronarde D, McCormick M, Parkinson H, Rosenthal PB, Saalfeld S, Saibil HR, Sarntivijai S, Solanes Valero I, Subramaniam S, Swedlow JR, Tudose I, Winn M, Kleywegt GJ.
Building bridges between cellular and molecular structural biology.
Elife. 2017 Jul 6;6. pii: e25835. doi: 10.7554/eLife.25835.

Pubmed

Earl LA, Falconieri V, Milne JLS, and Subramaniam S.
Cryo-EM: beyond the microscope.
Curr Opin Struct Biol. 2017 Jun 21;46:71-78. doi:10.1016/j.sbi.2017.06.002.

Pubmed

Glancy B, Hartnell LM, Combs CA, Fenmou A, Sun J, Murphy E, Subramaniam S, and Balaban RS.
Power Grid Protection of the Muscle Mitochondrial Reticulum.
Cell Rep. 2017 Apr 18;19(3):487-496. doi: 10.1016/j.celrep.2017.03.063.

Pubmed

Meyerson JR, Chittori S, Merk A, Rao P, Han TH, Serpe M, Mayer ML, and Subramaniam S.
Structural basis of kainate subtype glutamate receptor desensitization.
Nature. 2016 Sep 22;537(7621):567-571. doi: 10.1038/nature19352. Epub 2016 Aug 31.

Pubmed

Puppala AK, French RL, Matthies D, Baxa U, Subramaniam S, and Simonović M.
Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase.
Sci Rep. 2016 Aug 31;6:32563. doi: 10.1038/srep32563.

Pubmed

Subramaniam S, Earl LA, Falconieri V, Milne JLS, and Egelman EH.
Resolution advances in cryo-EM enable application to drug discovery.
Curr Opin Struct Biol. 2016 Dec;41:194-202. doi: 10.1016/j.sbi.2016.07.009. Epub 2016 Aug 20.

Pubmed

Earl LA and Subramaniam S.
Cryo-EM of viruses and vaccine design.
Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):8903-5. doi: 10.1073/pnas.1609721113. Epub 2016 Aug 1.

Pubmed

Stuart DI, Subramaniam S, and Abrescia NGA.
The democratization of cryo-EM.
Nat Methods. 2016 Jul 28;13(8):607-8. doi: 10.1038/nmeth.3946.

Pubmed

Pages